1974

SANGI Co., Ltd. established in Tokyo by Shuji

1976

NASA patent acquired

1978

Subsidiary Dental Kagaku Co., Ltd. established to produce hydroxyapatite

1980

Central Research Laboratory established

World’s first hydroxyapatite remineralizing toothpaste “APADENT” launched

1985

Subsidiary Apatite Co., Ltd. established to handle sales

Success of anticaries field trials among Japanese schoolchildren

Second toothpaste brand ”APAGARD” launched

1989

Antimicrobial agent "Apacider" launched

1992

“Denta Apato” brand launched for co-op route sales.

1993

Sangi’s proprietary hydroxyapatite approved as an active anticaries ingredient, “Medical Hydroxyapatite.” (<mHAP>)

1995

TV advertising : SANGI's toothpaste captures 20% Japanese market share

Apatite Co., Ltd. and Dental Kagaku Co., Ltd. merged into Sangi Co., Ltd.

1996

Relocation and expansion of Central Research Laboratory

1998

Health drink "Okara-cha" launched

2003

<mHAP> reduced from 3-figure to 2-figure nanoparticle size, enhancing remineralization and natural whitening capability

2004

“Renamel” brand launched exclusively for the dental route

2005

SANGI's hydroxyapatite catalyst project (ethanol to butanol) awarded a development grant from Japan's New Energy and Industrial Technology Development Organization (NEDO)

2006

Sangi exhibits for the first time at the International Association for Dental Research (IADR) as pioneer of hydroxyapatite toothpastes

2007

SANGI's 70th hydroxyapatite-related patent registered

2009

ISO 9001:2000 certification
Launch of Sangi’s Japanese online shop

2010

SANGI's next-generation hydroxyapatite powder jet deposition project (PJD), in conjunction with Tohoku University, awarded a 4-year development grant from Japan's Science and Technology Agency (JST)

2011

Toothpaste exports begin, initially to Russia (APADENT and later APAGARD)

2013

Toothpaste exports expand to Canada (OEM brand)

2014

APAGARD's 20th successive year as top-selling brand in Japan’s high-end “esthetic whitening” toothpaste market segment

2015

Toothpaste exports expand to China and Southeast Asia (both brands)

APAGARD Premio awarded the first Most Popular Toothpaste ranking by Japan's top consumer product opinion site @cosme

2017

Establishment of subsidiary SANGI Europe GmbH

APAGARD Premio awarded Hall of Fame status by Japan's top consumer product-ranking site, @Cosme, after being ranked Most Popular Toothpaste by consumers for 3 successive years.

2018

Launch of sales in the EU (both brands)

SANGI sponsors the first Nano-Hydroxyapatite in Dentistry Symposium at the IADR meeting in London

Launch of SANGI's skincare brand HAP+R in Japan

2019

SANGI's nano-hydroxyapatite remineralizing toothpaste sales since 1980 top 150 million tubes

2020

SANGI's export destinations reach 19 countries

SANGI EU online-shop launched

2021

Launch of Sangi's first medical device for dental use “APASHIELD” (anti-hypersensitivity agent)